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Life Extension

When Less Is More: How Mitochondrial Signals Extend Lifespan

January 8, 2011 Life Extension

In making your pro-longevity resolutions, like drinking more red wine and maintaining a vibrant social network, here’s one you likely forgot: dialing down your mitochondria. It turns out that slowing the engines of these tiny cellular factories could extend your life-an observation relevant not only to aging research but to our understanding of how cells communicate with each another.

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Eating Healthier Means Living Longer

December 23, 2010 Life Extension

The leading causes of death have shifted from infectious diseases to chronic diseases such as cardiovascular disease and cancer. These illnesses may be affected by diet. In a study published in the January 2011 issue of the Journal of the American Dietetic Association, researchers investigated empirical data regarding the associations of dietary patterns with mortality through analysis of the eating patterns of over 2500 adults between the ages of 70 and 79 over a ten-year period.

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‘Un-Growth Hormone’ Increases Longevity, Researchers Find

December 23, 2010 Life Extension

A compound which acts in the opposite way as growth hormone can reverse some of the signs of aging, a research team that includes a Saint Louis University physician has shown. The finding may be counter-intuitive to some older adults who take growth hormone, thinking it will help revitalize them.Their research was published in the Dec. 6 online edition of the Proceedings of the National Academy of Sciences.

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Free Radicals Good for You? Banned Herbicide Makes Worms Live Longer

December 21, 2010 Life Extension

It sounds like science fiction – Dr. Siegfried Hekimi and his student Dr Wen Yang, researchers at McGill’s Department of Biology, tested the current “free radical theory of aging” by creating mutant worms that had increased production of free radicals, predicting they would be short-lived. But they lived even longer than regular worms! Moreover, their enhanced longevity was abolished when they were treated with antioxidants such as vitamin C.

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Compound Derived From Curry Spice Is Neuroprotective Against Stroke And Traumatic Brain Injury

December 16, 2010 Cognitive Function

A synthetic derivative of the curry spice turmeric, made by scientists at the Salk Institute for Biological Studies, dramatically improves the behavioral and molecular deficits seen in animal models of ischemic stroke and traumatic brain injury (TBI). Two new studies suggest that the novel compound may have clinical promise for these conditions, which currently lack good therapies.

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Despite Longer Life Spans, Fewer Years Are Disease-Free

December 13, 2010 Life Extension

Increased life expectancy in the United States has not been accompanied by more years of perfect health, reveals new research published in the December issue of the Journal of Gerontology. Indeed, a 20-year-old today can expect to live one less healthy year over his or her lifespan than a 20-year-old a decade ago, even though life expectancy has grown.

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For Elderly, Even Short Falls Can Be Deadly; Adults 70-Plus Three Times As Likely To Die Following Low-Level Falls

December 7, 2010 Life Extension

While simple falls, such as slipping while walking off a curb, may seem relatively harmless, they can actually lead to severe injury and death in elderly individuals, according to a new study published in The Journal of Trauma: Injury, Infection, and Critical Care.

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Racing Against Age: Health Impairment Primarily Due To Bad Lifestye Habits — Not Aging, Researchers Argue

December 7, 2010 Life Extension

Impairments to health and physical performance are not primarily a result of aging but of unfavorable lifestyle habits and lack of exercise. This is the position taken by Dieter Leyk and his coauthors in the new issue of Deutsches Ärzteblatt International.

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New Method For Preventing Oxidative Damage To Cells: Findings Could Lead To Enhanced Health Supplements, Progress On Parkinson’s

December 6, 2010 Cardiovascular Research

The discovery by UCLA biochemists of a new method for preventing oxidation in the essential fatty acids of cell membranes could lead to a new class of more effective nutritional supplements and potentially help combat neurodegenerative disorders such as Parkinson’s disease and perhaps Alzheimer’s.

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New Method For Preventing Oxidative Damage To Cells: Findings Could Lead To Enhanced Health Supplements, Progress On Parkinson’s

December 6, 2010 Cognitive Function

The discovery by UCLA biochemists of a new method for preventing oxidation in the essential fatty acids of cell membranes could lead to a new class of more effective nutritional supplements and potentially help combat neurodegenerative disorders such as Parkinson’s disease and perhaps Alzheimer’s.

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Longevity Breakthrough: Scientists ‘Activate’ Life Extension In Worm, Discover Mitochondria’s Metabolic State Controls Life Span

December 1, 2010 Life Extension

If you think life’s too short, then you’re not alone. A team of scientists set out to find what it would take to live a very long life and they made important discoveries that bring longer life spans much closer to reality. A new research report featured on the cover of The FASEB Journal, describes how scientists “activated” life extension in the roundworm C. elegans, and in the process discovered a new metabolic state correlating with long life.

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Scientists Ferret Out A Key Pathway For Aging

November 18, 2010 Life Extension

For decades, scientists have been searching for the fundamental biological secrets of how eating less extends lifespan. It has been well documented in species ranging from spiders to monkeys that a diet with consistently fewer calories can dramatically slow the process of aging and improve health in old age.

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